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车志平
 

      车志平,博士、副教授、硕士生导师,河南省高校青年骨干教师,河南科技大学优秀教师、优秀党员、优秀学业导师。

近几年,以第一或通讯作者在Journal of Agricultural and Food Chemistry》、《Chemistry-A European Journal》、《Bioorganic & Medicinal Chemistry Letters》、《Industrial Crops and Products》、《Chemistry & Biodiversity》、《Combinatorial Chemistry & High Throughput Screening》、《Heterocycles》、《Natural Product Communications》、《Journal of Asian Natural Products Research》、《HortScience》和《化学通报等期刊发表学术论文61篇,其中SCI论文31篇;授权发明专利7项,实审发明专利12项;获省部级奖励2项(2018年获陕西省科学技术二等奖一项,2017年获河南省科技进步三等奖一项;指导大学生“挑战杯”获校级一等奖、省级二等奖,指导大学生重点科学创新研究项目2项,考核优秀。

一、学习经历

1.    2010.092013.06  西北农林科技大学 理学院 博士

2.    2007.092010.06  西北农林科技大学 植物保护学院 硕士

3.    2003.092007.07  河南科技大学 林学院 本科

二、工作经历

1.   2020.09-至今    河南科技大学 园艺与植物保护学院 副教授 科研秘书

2.   2018.012020.09  河南科技大学 林学院 副教授

3.   2013.072017.12  河南科技大学 林学院 讲师

三、研究方向

1.  植物源农用活性化合物结构优化、构效关系及作用机理研究

2.  基于植物源农用活性化合物为先导的新农药半合成研究

四、主持主要科研和人才项目

1. “基于植物次生物质奎宁为先导的结构优化及杀虫构效关系研究”,国家自然科学基金项目,2017.012019.1247万)

2.   基于结构多样性合成策略进行Cinchonamine结构优化及其杀虫活性和构效关系研究”河南科技大学青年学术带头人项目,2017.032020.0330万)

3. 基于丹皮酚的新农药创制及其应用研究”,河南省科技公关项目,2020.012021.1210万)

五、荣誉称号和学术兼职

1.   河南省优秀科技特派员(2018

2.   河南科技大学青年学术带头人(2016

3.   河南省植物病理学会学术与编辑工作委员会委员

六、代表性研究论文

1.  Che Zhiping*, Yang Jinming, Sun Di, Tian Yuee, Liu Shengming, Lin Xiaomin, Jiang Jia, Chen Genqiang, Synthesis of novel (9S)-acyloxy derivatives of quinidine and dihydroquinidine as insecticidal agents, Chemistry & Biodiversity, 2020, 17(4): e1900696

2.  Che Zhiping*, Yang Jinming, Sun Di, Tian Yuee, Liu Shengming, Lin Xiaomin, Jiang Jia, Chen Genqiang, Combinatorial synthesis of novel 9R-acyloxyquinine derivatives as insecticidal agents, Combinatorial Chemistry & High Throughput Screening, 2020, 23(2): 111-118

3.  Che Zhiping*, Yang Jinming, Sun Di, Tian Yuee, Liu Shengming, Lin Xiaomin, Jiang Jia, Chen Genqiang, Combinatorial synthesis of a series of paeonol-based phenylsulfonyl hydrazone derivatives as insecticidal agents, Combinatorial Chemistry & High Throughput Screening, 2020, 23(3): 232-238

4.  Che Zhiping*, Yang Jinming, Zhang Song, Sun Di, Tian Yuee, Liu Shengming, Lin Xiaomin, Jiang Jia, Chen Genqiang, Synthesis of novel 9R/S-acyloxy derivatives of cinchonidine and cinchonine as insecticidal agents, Journal of Asian Natural Products Research, 2020, DOI: 10.1080/10286020.2020.1729136

5.  Tian Yuee, Sun Di, Han Xiaoxiao, Yang Jinming, Zhang Song, Feng Nannan, Zhu Lina, Xu Zhongyuan, Che Zhiping*, Liu Shengming, Lin Xiaomin, Jiang Jia, Chen Genqiang, Synthesis, anti-oomycete activity, and SAR studies of paeonol derivatives, Journal of Asian Natural Products Research, 2020, DOI: 10.1080/10286020.2020.1718116

6.  Chen Genqiang, Sun Di, Yang Jinming, Zhang Song, Tian Yuee*, Che Zhiping*, Liu Shengming, Jiang Jia, Lin Xiaomin, Synthesis of sulfonate derivatives of carvacrol and thymol as anti-oomycetes agents, Journal of Asian Natural Products Research, 2020, DOI: 10.1080/10286020.2020.1758675

7.  Tian Yuee, Sun Di, Yang Jinming, Che Zhiping*, Liu Shengming, Lin Xiaomin, Jiang Jia, Chen Genqiang, Synthesis of sulfonate derivatives of maltol and their biological activity against Phytophthora capsici and Bursaphelenchus xylophilus in vitro, Journal of Asian Natural Products Research, 2020, 22(6): 578-587

8.  Che Zhiping*, Yang Jinming, Shan Xijie, Tian Yuee, Liu Shengming, Lin Xiaomin, Jiang Jia, Hu Mei, Chen Genqiang, Synthesis and insecticidal activity of sulfonate derivatives of sesamol against Mythimna separata in vivo, Journal of Asian Natural Products Research, 2019, 22(7): 678-688

9.  Che Zhiping*, Tian Yuee, Liu Shengming, Jiang Jia, Hu Mei, Chen Genqiang, Stereoselective synthesis of 4β-acyloxypodophyllotoxin derivatives as insecticidal agents, Journal of Asian Natural Products Research, 2019, 21(10): 1028-1041

10.  Che Zhiping*, Tian Yuee, Yang Jinming, Liu Shengming, Jiang Jia, Hu Mei, Chen Genqiang, Screening of insecticidal activity of podophyllotoxin analogues against Athetis dissimilis, Natural Product Communications, 2019, 14(1): 117-120

11.  Chen Genqiang, Xia Yanfei, Yang Jinming, Che Zhiping*, Sun Di, Li Shen, Tian Yuee, Liu Shengming, Jiang Jia, Lin Xiaomin, Controlled synthesis of N, N-dimethylarylsulfonamide derivatives as nematicidal agents, Journal of Asian Natural Products Research, 2019, DOI: 10.1080/10286020.2019.1694513

12.  Tian Yuee*, Che Zhiping(共同第一), Sun Di, Yang Yuanyuan, Lin Xiaomin, Liu Shengming, Liu Xiaoyu, Gao Jie, Resistance identification of tree peony cultivars of different flowering time to gray mold pathogen Botrytis cinerea, HortScience, 2019, 54(2): 328-330

13.  Tian Yuee*, Che Zhiping, Sun Di, He Jiaxuan, Liu Shengming, Lin Xiaomin, In vitro effects of five different classes of fungicides on growth and development of Botrytis cinerea isolated from tree peony in China, HortScience, 2019, 54(11):1984-1988

14.  Che Zhiping*, Tian Yuee, Liu Shengming, Jiang Jia, Hu Mei, Chen Genqiang, Microwave-assisted expeditious synthesis of 2-alkyl-2-(N-arylsulfonylindol-3-yl)-3-N-acyl-5-aryl-1,3,4-oxadiazolines catalyzed by HgCl2 under solvent-free conditions as potential anti-HIV-1 agents, Molecules, 2018, 23(11), 2936

15.  Che Zhiping, Tian Yuee, Liu Shengming, Hu Mei, Chen Genqiang*, Discovery of N-arylsulfonyl-3-acylindole benzoyl hydrazine derivatives as anti-HIV-1 agents, Brazilian Journal of Pharmaceutical Sciences, 2018, 54(4): e17543

16. Che Zhiping, Tian Yuee, Liu Shengming, Hu Mei, Chen Genqiang*, Synthesis and in vitro anti-HIV-1 evaluation of some N-arylsulfonyl-3-formylindoles, Brazilian Journal of Pharmaceutical Sciences, 2018, 54(3): e17044

17. Yu Xiang, Che Zhiping(共同第一), Xu Hui*, Recent advances in the chemistry and biology of podophyllotoxins, Chemistry-A European Journal, 2017, 23(19): 4467-4526

18. Yang Ruige, Huang Xiaobo, Che Zhiping(共同第一), Zhang Yuanyuan, Xu Hui*, Application of sustainable natural resources in crop protection: Podophyllotoxin-based botanical pesticides derived from Podophyllum hexandrum for controlling crop-threatening insect pests, Industrial Crops & Products, 2017, 107: 45-53

19. Che Zhiping, Tian Yuee, Hu Zhenjie, Chen Yingwu, Liu Shengming, Chen Genqiang*, Synthesis and in vitro anti-HIV-1 activity of a series of N-arylsulfonyl-3-propionylindoles, Zeitschrift für Naturforschung Section C-A Journal of Biosciences, 2016, 71(5-6)c: 105-109

20. Che Zhiping, Liu Shengming, Tian Yuee, Hu Zhenjie, Chen Yingwu, Chen Genqiang*, Design and synthesis of novel N-arylsulfonyl-3-(2-yl-ethanone)-6-methylindole derivatives as inhibitors of HIV-1 replication, Pharmaceuticals (Basel), 2015, 8(2): 221-229

21. Che Zhiping, Yu Xiang, Zhi Xiaoyan, Fan Lingling, Yao Xiaojun, Xu Hui*, Synthesis of novel 4α-(acyloxy)-2'(2',6')-(di)halogenopodophyllotoxin derivatives as insecticidal agents, Journal of Agricultural and Food Chemistry, 2013, 61(34): 8148-8155

22. Che Zhiping, Zhang Shaoyong, Shao Yonghua, Fan Lingling, Xu Hui*, Yu Xiang, Zhi Xiaoyan, Yao Xiaojun, Zhang Rui, Synthesis and quantitative structure-activity relationship (QSAR) study of novel N-arylsulfonyl-3-acylindole arylcarbonyl hydrazone derivatives as nematicidal agents, Journal of Agricultural and Food Chemistry, 2013, 61(24): 5696-5705

23. Che Zhiping, Yu Xiang, Fan Lingling, Xu, Hui*, Insight into dihalogenation of E-ring of podophyllotoxins, and their acyloxyation derivatives at the C4 position as insecticidal agents, Bioorganic & Medicinal Chemistry Letters, 2013, 23(20): 5592-5598

24. Che Zhiping, Huang Ning, Yu Xiang, Yang Liumeng, Ran Junqiang, Zhi Xiaoyan, Xu Hui*, Zheng Yongtang*, Microwave-assisted combinatorial synthesis of 2-alkyl-2-(N-arylsulfonylindol-3-yl)-3-N-acyl-5-aryl-1,3,4-oxadiazolines as anti-HIV-1 agents, Combinatorial Chemistry & High Throughput Screening, 2013, 16(5): 400-407

25. 车志平*, 杨进明, 田月娥, 刘圣明, 姜佳, 陈根强, 奎宁类化合物研究进展, 化学通报, 2018, 81(9): 792-796+804

七、联系方式

地址:河南省洛阳市洛龙区开元大道263 河南科技大学 园艺与植物保护学院

邮编:471023

Emailzhipingche@163.com / czpgsts@haust.edu.cn

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河南科技大学 园艺与植物保护学院   |    地址:中国·洛阳 开元大道263号   |   邮编:471023   |   联系电话:0379-64282345

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